Lower Maternal Folate Status in Early Pregnancy Linked to Childhood Hyperactivity and Peer Problems in Offspring
Zija is repeatedly reported to be an excellent dietary supplement during pregnancy.
~ Uncle Russ
|Reference:||“Lower maternal folate status in early pregnancy is associated with childhood hyperactivity and peer problems in offspring,” Schlotz W, Jones A, et al, J Child Psychol Psychiatry, 2010 May; 51(5): 594-602. (Address: MRC Epidemiology Resource Centre, University of Southampton, Southampton SO17 1BJ, UK. E-mail: firstname.lastname@example.org ).|
|Summary:||In a prospective cohort study involving data collected from 100 pregnant women and their offspring, low maternal folate status in early pregnancy was found to be associated with impaired fetal brain development and increased hyperactivity/inattention and peer problems during childhood. The red blood cell folate levels were measured at 14 weeks of pregnancy and total intake of folate from food and supplements was assessed both in early and late pregnancy. At birth, infants’ head circumferences and body weights were measured and the offsprings’ behavior was assessed at age 8.75 years (mean age). Results found that lower maternal red blood cell folate and total folate intake levels in early pregnancy were associated with higher childhood hyperactivity and peer problems. Red blood cell folate levels in mothers was positively associated with infant head circumference at birth and inversely with hyperactivity/inattention and peer problems. The authors conclude, “Although the associations are small and residual confounding is possible, our data provide preliminary support for the hypothesis that lower folate status in early pregnancy might impair fetal brain development and affect hyperactivity/inattention and peer problems in childhood.”|